Boron neutron capture therapy assisted by boron-conjugated nanoparticles
نویسندگان
چکیده
منابع مشابه
Boron Neutron Capture Therapy
A project aimed at the development of an accelerator facility devoted to Boron Neutron Capture Therapy (BNCT) is ongoing at the National Atomic Energy Commission of Argentina [1]. In a first stage of development, the accelerator will be capable of delivering proton or deuteron beams of 30 mA at about 1.4 MeV which is suitable for neutron production through the 9Be(d,n) reaction. In this context...
متن کاملPharmacokinetics of core-polymerized, boron-conjugated micelles designed for boron neutron capture therapy for cancer.
Core-polymerized and boron-conjugated micelles (PM micelles) were prepared by free radical copolymerization of a PEG-b-PLA block copolymer bearing an acetal group and a methacryloyl group (acetal-PEG-b-PLA-MA), with 1-(4-vinylbenzyl)-closo-carborane (VB-carborane), and the utility of these micelles as a tumor-targeted boron delivery system was investigated for boron neutron capture therapy (BNC...
متن کاملBoron Neutron Capture Therapy: Delivery Agents Used in Boron Administration
25 Laurentia Gales 258 Șos.Fundeni, 2nd District, Bucharest, Romania e-mail: [email protected] Abstract. Boron neutron capture theory (BNCT) is a binary therapy applied in malignant tumours, resistant to other treatment methods, namely chemotherapy and radiotherapy. One of the main components is Bor-10, a stable isotope that can be inserted in the tumour cells by using specific transpor...
متن کاملشبیه سازی چشمه 7li(p,n)7be جهت استفاده در bnct (boron neutron capture therapy)
با توجه به اینکه امروزه بیماران بسیاری در سراسر جهان از سرطان رنج میبرند،دانشمندان در تلاشند روشهای درمانی جدیدتر و بهتری را کشف کنند .یکی از این روشها "درمان بوسیله گیراندازی نوترون توسط بور (bnct)" نام دارد که میتواند یکی از بهترین روشهای مفید و موثر و جایگزین در درمان سرطانهایی از نوع glioblastoma و melanoma نسبت به روشهای متداولی چون شیمی درمانی یا رادیوتراپی باشد.در این روش هدف انجام واکنش...
Boron Neutron Capture Therapy Treatment Planning Improvements
The Boron Neutron Capture Therapy (BNCT) treatment planning process of the Harvard/MIT team used for their clinical Phase I trials is very time consuming. If BNCT proves to be a successful treatment, this process must be made more efficient. Since the Monte Carlo treatment planning calculations were the most time consuming aspect of the treatment planning process, requiring more than thirty six...
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ژورنال
عنوان ژورنال: Polymer Journal
سال: 2012
ISSN: 0032-3896,1349-0540
DOI: 10.1038/pj.2012.30